Rajkumar Manickam | Karpagam Academy of Higher Education | India
Dr. Rajkumar Manickam is an Assistant Professor in the Department of Biotechnology at Karpagam Academy of Higher Education, India. His research spans nanotechnology, molecular biology, and biomedical applications, with a focus on the green synthesis and characterization of biopolymer-based nanocomposite biomaterials for therapeutic use in neurodegenerative diseases. He has expertise in advanced material characterization, in vitro and in vivo experimental models, and in silico molecular docking studies. Dr. Rajkumar has earned multiple research awards and recognition for his contributions to functional materials and biomedical science.
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Summary:
Dr. Rajkumar’s eco-friendly nanomaterial research holds significant potential for soil biodiversity conservation through reduction of harmful agrochemicals and development of biocompatible soil amendments. His interdisciplinary background positions him well to bridge the gap between material science and soil ecology. With strategic alignment of his work toward soil microbial conservation and ecosystem restoration, his contributions could have a meaningful impact on sustainable agriculture and soil health.
Education
Dr. Manickam Rajkumar holds a Doctor of Philosophy in Zoology from Periyar University, along with an M.Phil., M.Sc., and B.Sc. in Zoology. He has completed his Post-Doctoral Fellowship in Chemistry at SSN College of Engineering, Anna University, and currently serves as an Assistant Professor in the Department of Biotechnology at Karpagam Academy of Higher Education, Tamil Nadu, India.
Experience
His expertise spans nanotechnology, molecular biology, in vivo experimentation, and biomedical applications. In nanotechnology, his work focuses on synthesizing nanocomposite biomaterials from organic and inorganic compounds and studying their properties using advanced characterization techniques including UV-visible spectrophotometry, FT-IR, XRD, FE-SEM-EDX, and HR-TEM, alongside physical property assessments such as swelling behavior and in vitro drug release studies. His molecular biology research encompasses in vitro, in vivo, and in silico investigations, emphasizing cell culturing, drug treatment, cell viability assays, MTT analysis, western blotting, SDS-PAGE, AGE, and fluorescent microscopy for cell apoptosis, ROS detection, and mitochondrial staining. His in vivo experimental experience includes animal handling, behavioral assessments using Morris water maze, passive avoidance, and Y-maze tests, as well as biochemical and histopathological analyses. In biomedical applications, he has explored antibacterial, antioxidant, anticholinesterase, anti-inflammatory, anti-diabetic, and wound-healing activities.
Research Focus
He possesses strong skills in nanocomposite biomaterials synthesis, advanced material characterization, cell culture techniques, molecular biology assays, animal handling and behavioral testing, histopathological and immunohistochemical analysis, and the design and execution of in vitro, in vivo, and in silico experiments. He is also proficient in assessing a wide range of biomedical activities, including antimicrobial, antioxidant, and anti-inflammatory effects.
Awards
He has been honored with the University Research Fellowship from Periyar University and has received multiple recognition awards, including the Best Oral Presentation Award at the DST-SERB Sponsored Third International Conference on Functional Materials for NextGen Applications, the Best Poster Presentation Award at the International Conference on Nano Structured Materials and Nanocomposites, and the Best Oral Presentation Award at the International Conference on Multifunctional Advanced Materials.
Publications
Title: Eco-friendly synthesis of zinc oxide nanoparticles using Caralluma adscendens stem extract: Characterization, antibacterial, antioxidant, and cytotoxic effects of breast cancer cells
Authors: Chinnasamy Ragavendran, Chinnaperumal Kamaraj, Mir Waqas Alam, Manickam Rajkumar
Year: 2025
Journal: Inorganic Chemistry Communications
Title: Unrevealing biosynthesis of zinc oxide nanoparticles using Laggera alata leaf extract: Evaluation of antioxidant, anticholinergic, and anti-diabetic properties
Authors: Periyasamy Visvanathan, Dharmalingam Kirubakaran, Manickam Rajkumar, Alagarsamy Shanmugarathinam, Magudeeswaran Sivanandam
Year: 2025
Journal: Biomedical Materials & Devices
Title: Magnetic nanoparticles of Fe₃O₄ biosynthesis using Anacardium occidentale fruit extract: Evaluation of in vitro antioxidant, antibacterial, antidiabetic, anti-cholinesterase and cytotoxic activities
Authors: Manickam Rajkumar, S.I. Davis Presley, M. Yasmin Begum, Ali Alamri, Adel Al Fatease, Prabha Govindaraj, Krishnan Meenambigai, Chinnasamy Ragavendran
Year: 2025
Journal: Inorganic Chemistry Communications
Title: Biosynthesis of cerium oxide nanoparticles using Alternanthera sessilis leaf extract and evaluation of their antioxidant, antibacterial, anti-inflammatory, antidiabetic and cytotoxic activities
Authors: Manickam Rajkumar, S.I. Davis Presley, Prabha Govindaraj, Krishnan Meenambigai, Thandapani Gomathi, Musab Mohammad Al-Essa, Farid Menaa
Year: 2025
Journal: Biomedical Materials & Devices
Title: Analyze and assess the spectral, DFT, and medicinal characteristics through targeted pharmacological investigation of 2-(3-(5-(4-chlorophenyl)furan-2-yl)acryloyl)-3,4-dihydro-2H-naphthalen-1-one (CHFADN)
Authors: J. Irshad Ahamed, S.I. Davis Presley, Jothi Ramalingam Rajabathar, V.O. Sangeetha, Venkatadri Babu, Manickam Rajkumar, Manjunath S. Kamath
Year: 2025
Journal: Journal of Molecular Structure
Title: A comprehensive review on the green synthesis of nanoparticles: Advancements in biomedical and environmental applications
Authors: Dharmalingam Kirubakaran, Jamith Basha Abdul Wahid, Natchimuthu Karmegam, Ravisankar Jeevika, Latha Sellapillai, Manickam Rajkumar, K.J. SenthilKumar
Year: 2025
Journal: Biomedical Materials & Devices
Dr. Rajkumar Manickam is a promising candidate for the Soil Biodiversity Conservation Award, particularly for his commitment to green synthesis and plant-based nanotechnological innovations. While further direct application to soil biodiversity restoration would strengthen his candidacy, his scientific excellence, eco-friendly methodologies, and global research visibility make him a strong contender who could significantly contribute to sustainable soil management and biodiversity preservation.