Dr. Xiaobo Zhong | Soil Biology | Distinguished Soil Science Achievement

Dr. Xiaobo Zhong | Institut Pasteur | France 

Dr. Xiaobo Zhong is a microbiologist whose research explores the structural and molecular mechanisms that govern bacterial morphogenesis and intercellular interactions. His work focuses on the bacterial cell wall, a multifunctional structure critical for maintaining shape, division, and environmental adaptability. Through advanced techniques such as cryo-electron tomography, he investigates how bacterial cell surface architectures enable microbial communication and phenomena like microbial hitchhiking, where non-motile species utilize motile counterparts for dispersal. His studies have revealed key molecular players in cell wall biosynthesis, including cellulose synthase complexes and stomatin-like proteins that organize membrane microdomains under stress conditions. His research contributions, published in leading journals such as Nature Communications, Trends in Microbiology, and mBio, have expanded understanding of cell envelope biology and stress adaptation in filamentous actinobacteria. His work bridges structural biology, microbiology, and biochemistry, advancing insight into microbial physiology and antibiotic resistance. In addition to research, he has supervised and mentored graduate and undergraduate students and contributed to several international conferences through oral and poster presentations. His ongoing investigations at the Pasteur Institute continue to advance integrative structural cell biology with applications in microbial biotechnology and antibiotic discovery.

Profile:  Orcid 

Featured Publications

Zhong, X., & Claessen, D. (2025). Cellulose biosynthesis and function in Streptomyces. Trends in Microbiology.

Zhong, X., Baur, S. S. M., Ongenae, V. M. A., Guerrero Egido, G., Shitut, S., Du, C., Vijgenboom, E., van Wezel, G. P., Carrion Bravo, V., Briegel, A., & Claessen, D. (2025). The stomatin-like protein StlP organizes membrane microdomains to govern polar growth in filamentous actinobacteria under hyperosmotic stress. Nature Communications.

Zhong, X., Nicolardi, S., Ouyang, R., Wuhrer, M., Du, C., van Wezel, G. P., Vijgenboom, E., Briegel, A., & Claessen, D. (2024). CslA and GlxA from Streptomyces lividans form a functional cellulose synthase complex. Applied and Environmental Microbiology, 90(4), e02087-23.

Xiaobo Zhong | Soil Biology | Distinguished Soil Science Achievement

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